Guggulsterone from Guggul Tree Sap - This is an older (2002) article on the medicinal and chemical properties of a substance found in the sap or resin of the Asian Indian Guggul tree. The compound, called guggulsterone, blocks the FXR receptor (where?). The FXR receptor controls bile levels (and production) in the liver. By blocking the FXR receptor, the guggulsterone compound prevents the uptake/recycling of cholestrol laiden bile from the small intestine, thus breaking the metabolic cycle for bile. That's my best understanding from the article. May need more research. Sounds like the guggul sap is available in health food stores, particularly in India, where it's been used for the last 40 years to treat heart disease. Another "natural" remedy.

Guggul and Google...coincidence? How is Google like Guggul tree sap?

Ancient folk remedy may help control cholesterol

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