02:13 🔄 Similar paradoxical patterns exist with BMI, blood pressure, and hemoglobin A1c, where mortality risk increases as these health indicators move towards the normal range.
04:36 🚨 Low cholesterol in epidemiological studies may be a proxy for underlying diseases rather than a direct cause of increased mortality.
05:32 💊 Directly lowering cholesterol through interventions like statins or genetic factors does not show the same association with increased mortality.
08:16 🤔 The idea of keeping cholesterol high due to U-shaped curves in epidemiological studies is contradicted by robust evidence and lacks scientific support.